CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 24 enrolled
Drug / intervention
SWET: Supervised Weight loss and Exercise Training +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04356183
NCT04356183N/ACompleted
CompareCT.gov

Weight Loss and Exercise To Improve Rheumatoid Arthritis Cardiovascular Risk

Duke University·interventional·Posted Apr 22, 2020·Updated Mar 30, 2025

In Brief

A clinical study evaluating SWET: Supervised Weight loss and Exercise Training and CHAT: Counseling Health As Treatment for Rheumatoid Arthritis. Completed, enrolled 24 participants across 1 site.

Detailed Summary

This is a small exploratory, randomized, controlled trial. Twenty-six older (ages 60-80 yr.), obese (BMI 28-40 kg/m2) persons with rheumatoid arthritis (RA) (seropositive or erosive) will be randomized to 16 weeks of a counseling health as treatment (CHAT) program or a supervised weight loss and exercise training (SWET) program.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRheumatoid Arthritis
CountriesUnited States
CollaboratorsNational Institutes of Health (NIH), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedApr 22, 2020
Enrollment StartJul 21, 2021
Primary CompletionFeb 3, 2023
Study CompletionFeb 23, 2023
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 6.2 years ago

Interventions

SWET: Supervised Weight loss and Exercise Trainingother

Weight loss will occur via a dietitian-led intervention targeting weight loss over 16 weeks, with weekly weigh-ins and group support sessions. Exercise training will consist of three times per week of an interval-based aerobic program plus twice-weekly resistance training. Both weight loss and exercise training will be supervised to maximize safety and adherence.

CHAT: Counseling Health As Treatmentother

Control Arm over 16 weeks.