At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Environmental Localization Mapping and Guidance for Visual Prosthesis Users
In Brief
A clinical study evaluating Navigation system mode: Argus Vision, Navigation system mode: Depth Vision, and 7 other interventions for Retinitis Pigmentosa and 2 related conditions. Completed, enrolled 26 participants across 2 sites.
Detailed Summary
This study is driven by the hypothesis that independent navigation by blind users of visual prosthetic devices can be greatly aided by use of an autonomous navigational aid that provides information about the environment and guidance for navigation through multimodal sensory cues. For this study, the investigators developed a navigation system that uses on-board sensing to map the user's environment and compute navigable paths to desired destinations in real-time. Information regarding obstacles and directional guidance is communicated to the user via a combination of sensory modalities including limited vision (through the user's visual prosthesis), haptic, and audio cues. This study evaluates how effectively this navigational aid improves prosthetic vision users' ability to perform navigational tasks. The participants for this study include both retinal prosthesis users of the Argus II Retinal Prosthesis System (Argus II) and normally sighted individuals who use a virtual reality headset to simulate the limited vision of the Argus II system.
Study Details
Timeline
Interventions
This intervention uses the navigational aid with the output sensory modalities configured as follows: * Vision: Argus mode * Haptics: none * Audio: none Since this mode only provides the standard Argus vision, it is equivalent to using the base Argus II system without the navigational aid.
This intervention uses the navigational aid with the output sensory modalities configured as follows: * Vision: Depth mode (at Argus II resolution and field-of-view) * Haptics: none * Audio: none
This intervention uses the navigational aid with the output sensory modalities configured as follows: * Vision: Depth mode (at Argus II resolution and field-of-view) * Haptics: yes * Audio: yes
This intervention uses the navigational aid with the output sensory modalities configured as follows: * Vision: none * Haptics: yes * Audio: yes Since this mode does not provide any visual feedback, it is equivalent to using navigational aid completely blind without a visual prosthesis.
This intervention uses the navigational aid with the output sensory modalities configured as follows: * Vision: High Field-of-View Depth mode (at twice the Argus II resolution and field-of-view along each dimension) * Haptics: none * Audio: none
This intervention performs the relative distance to two obstacles test with the user's vision output configured as follows: * Resolution: Low * Field-of-View: Low
This intervention performs the relative distance to two obstacles test with the user's vision output configured as follows: * Resolution: Low * Field-of-View: High
This intervention performs the relative distance to two obstacles test with the user's vision output configured as follows: * Resolution: High * Field-of-View: Low
This intervention performs the relative distance to two obstacles test with the user's vision output configured as follows: * Resolution: High * Field-of-View: High