At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Yellow Micropulse Laser 577-nm vs Infrared Diode Micropulse Laser 810-nm for the Treatment of Diabetic Macular Edema
In Brief
A Phase 4 clinical trial evaluating Yellow micro-pulse laser and Diode micro-pulse laser for Diabetic Retinopathy and Macula Edema. Completed, enrolled 15 participants across 1 site.
Detailed Summary
Anti-vascular endothelial growth factor (VEGF) therapy is currently the mainstay of treatment for diabetic macular edema (DME). One of the main obstacles of anti-VEGF therapy is the need of repeated injections, which carries both economic and compliance problems to the patients.there is a growing evidence that recognises the effectiveness of the use of micropulse laser (MPL) in treatment of DME. with MPL, it is possible to deliver a subthreshold laser that is above the threshold of biochemical effect but below the threshold of a visible, destructive lesion thereby preventing collateral damage.The MPL technique is available at near - infrared 810 nm diode laser (diode MPL) and at 577 nm (yellow MPL). The current study was conducted in order to compare the efficacy of both MPL techniques in the treatment of center involving DME.
Study Details
Timeline
Interventions
applying 577-nm yellow laser in a micro-pulse mode over the macular area including the fovea
applying 810-nm infra-red diode laser in a micro-pulse mode over the macular area including the fovea