CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 195 enrolled
Drug / intervention
Endometrial scratch with Pipelle curette +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04363879
NCT04363879N/ACompleted

Comparing Two Types of Endometrial Activation Prior to Embryo Transfer: A Pilot Study

Wake Forest University Health Sciences·interventional·Posted Apr 27, 2020·Updated Oct 20, 2022

In Brief

A clinical study evaluating Endometrial scratch with Pipelle curette and Endometrial scratch with Shepard catheter for Infertility and Endometrial Disorder. Completed, enrolled 195 participants.

Detailed Summary

To determine if two types of endometrial activation (Pipelle curette or Shepard catheter) prior to embryo transfer result in similar live birth rates. Also to determine if patients experience similar pain from both types of endometrial activation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
Countries--
Collaborators--

Timeline

N/ACompletedFinished
201520162017201820192020202120222023202420252026
First PostedApr 27, 2020
Enrollment StartJun 16, 2014
Primary CompletionJul 1, 2017
TodayJul 2, 2026
Enrollment to primary: 3.0 yearsPosted 6.2 years ago

Interventions

Endometrial scratch with Pipelle curetteprocedure

For patients in the Pipelle curette group, physicians inserted the Pipelle curette into the uterus and removed an adequate endometrial sample using vigorous motion.

Endometrial scratch with Shepard catheterprocedure

For patients in the Shepard catheter group, physicians performed a four-quadrant scratch technique by inserting the Shepard insemination catheter into the uterus at 12:00. The catheter was then turned one-quarter turn and withdrawn. This was repeated two more times so that four endometrial quadrants were touched by the catheter at 12:00, 3:00, 6:00, and 9:00.