CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 39,363 enrolled
Drug / intervention
Order set review and modification with facilitation +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04366440
NCT04366440N/ACompleted

De-Implementation of Unnecessary Surgical Antibiotic Prophylaxis in Children

Washington University School of Medicine·interventional·Posted Apr 28, 2020·Updated Dec 10, 2024

In Brief

A clinical study evaluating Order set review and modification with facilitation and Order set review and modification for Surgical Site Infection. Completed, enrolled 39,363 participants across 10 sites.

Detailed Summary

The overall objective of this study is to identify the best strategy to eliminate unnecessary antibiotic use after surgery in pediatric surgical procedures considered low-risk for an SSI. Based on literature and our preliminary data suggesting surgeons will not fully accept standardized order sets based on current guidelines, the investigators hypothesize that order set modification combined with ASP facilitation will outperform standard order set modification alone in de-implementing unnecessary postoperative antibiotic use.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedApr 28, 2020
Enrollment StartNov 1, 2020
Primary CompletionFeb 1, 2024
Study CompletionNov 30, 2024
TodayJul 2, 2026
Enrollment to primary: 3.3 yearsPosted 6.2 years ago

Interventions

Order set review and modification with facilitationbehavioral

The antimicrobial stewardship program will receive facilitation training to aid in reviewing and changing order sets of clean or clean-contaminated procedures to eliminate unnecessary post-operative antibiotics.

Order set review and modificationother

The antimicrobial stewardship program will work to eliminate unnecessary post-operative antibiotics by reviewing and changing order sets of clean or clean-contaminated procedures.