CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 33 enrolled
Drug / intervention
Cigarette Smoker/ECIG users: 0 mg/ml nicotine concentration +3 moreother
Likely dose
Cigarette Smoker/ECIG users: 0 mg/ml nicotine concentrationfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04378907
NCT04378907N/ACompleted
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Assessing Electronic Cigarette Nicotine Flux

Virginia Commonwealth University·interventional·Posted May 7, 2020·Updated Feb 4, 2026

In Brief

A clinical study evaluating Cigarette Smoker/ECIG users: 0 mg/ml nicotine concentration, Cigarette Smokers/ECIG users: 6 mg/ml nicotine concentration, and 2 other interventions for Electronic Cigarette Use. Completed, enrolled 33 participants across 1 site.

Detailed Summary

The purpose of this study is to determine differences in nicotine delivery, use behavior, carbon monoxide delivery, subjective effects, and physiological effects, when cigarette smokers use an electronic cigarette with constant device settings and different e-liquid concentrations.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsElectronic Cigarette Use
CountriesUnited States
CollaboratorsNational Institute on Drug Abuse (NIDA)

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedMay 7, 2020
Enrollment StartJan 5, 2021
Primary CompletionFeb 1, 2023
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 6.2 years ago

Interventions

Cigarette Smoker/ECIG users: 0 mg/ml nicotine concentrationother

ECIG LAB SESSION: 30 watts, 0 mg/ml nicotine concentration. During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.

Cigarette Smokers/ECIG users: 6 mg/ml nicotine concentrationother

ECIG Lab Session, 30 watts, 6 mg/ml nicotine concentration. During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.

Cigarette Smokers/ECIG users: 15 mg/ml nicotine concentrationother

ECIG Lab Session, 30 watts, 15 mg/ml nicotine concentration. During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.

Cigarette Smokers/ECIG users: 30 mg/ml nicotine concentrationother

ECIG Lab Session, 30 watts, 30 mg/ml nicotine concentration During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.