CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 140 enrolled
Drug / intervention
MAS825 +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04382651
NCT04382651Phase 2Completed

A Phase 2, Randomized, Placebo-controlled, Participant and Investigator Blinded, Multi-center Study to Assess Efficacy and Safety of MAS825 for the Treatment of SARS-CoV-2 Infected Patients With COVID-19 Pneumonia and Impaired Respiratory Function

Novartis Pharmaceuticals·interventional·Posted May 11, 2020·Updated Aug 10, 2022

In Brief

A Phase 2 clinical trial evaluating MAS825, Placebo, and 1 other intervention for COVID-19 Pneumonia, Impaired Respiratory Function. Completed, enrolled 140 participants across 21 sites.

Detailed Summary

This clinical study was designed to assess the efficacy and safety of MAS825 for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) infected patients with coronavirus disease 2019 (COVID-19) pneumonia and impaired respiratory function.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
202120222023202420252026
First PostedMay 11, 2020
Enrollment StartJun 11, 2020
Primary CompletionJan 6, 2021
Study CompletionApr 21, 2021
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 6.1 years ago

Interventions

MAS825drug

MAS825 liquid solution for intravenous infusion

Placeboother

Placebo liquid solution for intravenous infusion

Standard of Care (SoC)drug

SoC included a variety of supportive therapies that ranged from the administration of supplementary oxygen to full intensive care support, alongside the use of antiviral treatment, convalescent plasma, corticosteroids, antibiotics or other agents.