CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 100 enrolled
Drug / intervention
Ganaxolone +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04391569
NCT04391569Phase 3Completed

A Double-blind, Randomized, Placebo-controlled Study to Evaluate the Efficacy and Safety of Intravenous Ganaxolone in Status Epilepticus

Marinus Pharmaceuticals·interventional·Posted May 18, 2020·Updated May 29, 2025

In Brief

A Phase 3 clinical trial evaluating Ganaxolone and Placebo for Status Epilepticus. Completed, enrolled 100 participants across 74 sites in 3 countries.

Detailed Summary

This study evaluated the effectiveness and safety of an investigational product (IP), intravenous (IV) ganaxolone, to treat participants with status epilepticus (SE).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Canada, United States
Collaborators--

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedMay 18, 2020
Enrollment StartDec 9, 2020
Primary CompletionMar 30, 2024
Study CompletionApr 28, 2024
TodayJul 2, 2026
Enrollment to primary: 3.3 yearsPosted 6.1 years ago

Interventions

Ganaxolonedrug

Ganaxolone will be administered.

Placebodrug

Placebo will be administered.