At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 718 enrolled
Drug / intervention
ECF843 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Randomized, Double-masked, Multicenter Study to Evaluate the Safety and Efficacy of ECF843 vs Vehicle in Subjects With Dry Eye Disease
In Brief
A Phase 2 clinical trial evaluating ECF843 and ECF843 vehicle for Dry Eye. Completed, enrolled 718 participants across 52 sites.
Detailed Summary
The study was planned to be conducted in 2 parts: Part 1 to determine the efficacy and safety of ECF843 vs vehicle, followed by Part 2 with additional exploratory assessments of ECF843 vs Vehicle. Both parts of the study included a double-masked study design, with randomization stratified for subjects with Sjogren's Syndrome.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDry Eye
CountriesUnited States
Collaborators--
Timeline
Phase 2CompletedFinished
202120222023202420252026
First PostedMay 2020
Enrollment StartOct 2020
Primary CompletionMay 2021
TodayJul 2026
First PostedMay 18, 2020
Enrollment StartOct 6, 2020
Primary CompletionMay 13, 2021
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 6.1 years ago
Interventions
ECF843drug
Topical ocular eye drop
ECF843 vehicleother
Topical ocular eye drop