CI

At a glance

ClinicalIndex Comparison Record
Phase 2Active· 173 enrolled
Drug / intervention
AB-106drug
Likely dose
AB-106 400mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04395677
NCT04395677Phase 2Active

A Multicenter, Open Label, Single Arm Phase 2 Study of AB-106 in the Treatment of Locally Advanced and Metastatic NSCLC

Nuvation Bio Inc.·interventional·Posted May 20, 2020·Updated Feb 6, 2026

In Brief

A Phase 2 clinical trial evaluating AB-106 for Non Small Cell Lung Cancer. Active but no longer recruiting, targeting 173 participants across 1 site.

Detailed Summary

The purpose of the study is to evaluate safety, pharmacokinetics and efficacy of AB-106 monotherapy in the treatment of advanced NSCLC.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

Phase 2Active
2021202220232024202520262027
First PostedMay 20, 2020
Enrollment StartJul 7, 2020
Primary CompletionJun 7, 2024
Study CompletionJun 1, 2027
TodayJul 2, 2026
Enrollment to primary: 3.9 yearsPosted 6.1 years ago

Interventions

AB-106drug

Stage 1: 400mg QD for 3 patients and 600mg QD for 3 patients Stage 2: 600mg QD