At a glance
ClinicalIndex Comparison RecordN/ACompleted· 240 enrolled
Drug / intervention
NGS + Antibiotic Recommendation +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Randomized Clinical Trial Using Next Generation Microbial Sequencing to Direct Antibiotic Selection Before Kidney Stone Lithotripsy Using an Interprofessional Model
The University of Texas Health Science Center at San Antonio·interventional·Posted May 28, 2020·Updated Mar 12, 2024
In Brief
A clinical study evaluating NGS + Antibiotic Recommendation and Standard of Care treatment for Kidney Stone and 2 related conditions. Completed, enrolled 240 participants across 3 sites.
Detailed Summary
This is a randomized controlled clinical study evaluating the use of next-generation sequencing (NGS) to improve antibiotic prescribing before ureteroscopy or percutaneous nephrolithotomy.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsKidney Stone, Renal Stone, Infection, Bacterial
CountriesUnited States
CollaboratorsMicrogen LLC
Timeline
N/ACompletedFinished
2020202120222023202420252026
Enrollment StartDec 2019
First PostedMay 2020
Primary CompletionJan 2022
Study CompletionAug 2022
TodayJul 2026
First PostedMay 28, 2020
Enrollment StartDec 18, 2019
Primary CompletionJan 31, 2022
Study CompletionAug 31, 2022
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 6.1 years ago
Interventions
NGS + Antibiotic Recommendationother
NGS results in addition to recommended antibiotic therapy made by infectious disease pharmacist
Standard of Care treatmentprocedure
Subjects will have a standard of care urine culture and prophylactic antibiotic prescribed per routine care.