At a glance
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Comparison of Non-Surgical Treatment Options for Chronic Exertional Compartment Syndrome (CECS)
In Brief
A Phase 2 clinical trial evaluating Supervised Gait Retraining, Home Based Gait Retraining, and 2 other interventions for Chronic Exertional Compartment Syndrome. Completed, enrolled 35 participants across 4 sites.
Detailed Summary
Chronic Exertional Compartment Syndrome (CECS) in the lower leg is a debilitating condition in highly active individuals. Pain occurs in 1 or several leg compartments upon an exertional activity, typically running, that quickly dissipates once the activity stopped. Surgical fasciotomy is the standard for treating lower leg CECS, but success is variable. Complications may occur post-surgery and there is a potential for a repeat procedure. Recovery times post-surgery also vary greatly. Conservative treatments, such as gait retraining and botulinum toxin injections, are emerging as non-surgical options for the treatment of CECS with success through published case reports and case series. This study aims to evaluate the use of these non-surgical treatment options for CECS in the anterior and lateral leg compartments with a follow up for at least 2 years across multiple study sites.
Study Details
Timeline
Interventions
The participants allocated to this group will attend 8 sessions during the course of 6 weeks in the clinic with a trained medical professional to complete a supervised gait retraining program.
The participants allocated to this group will have 1 session in the clinic with a trained medical professional and be given a gait retraining program to complete at home.
The participant will receive a saline injection to their painful lower leg compartment(s).
The participant will receive a botulinum toxin injection to their painful lower leg compartment(s).