CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 161 enrolled
Drug / intervention
CNM-Au8 +1 moredrug
Likely dose
CNM-Au8 30 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04414345
NCT04414345Phase 3Completed

HEALEY ALS Platform Trial - Regimen C CNM-Au8

Merit E. Cudkowicz, MD·interventional·Posted Jun 4, 2020·Updated Jul 25, 2023

In Brief

A Phase 3 clinical trial evaluating CNM-Au8 and Matching Placebo for Amyotrophic Lateral Sclerosis. Completed, enrolled 161 participants across 1 site.

Detailed Summary

The HEALEY ALS Platform Trial is a perpetual multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investigational products for the treatment of ALS. Regimen C will evaluate the safety and efficacy of a single study drug, CNM-Au8, in participants with ALS.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsClene Nanomedicine

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedJun 4, 2020
Enrollment StartJul 30, 2020
Primary CompletionApr 13, 2022
Study CompletionMar 7, 2023
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 6.1 years ago

Interventions

CNM-Au8drug

Drug: CNM-Au8 Administration: Oral Dosage: 30 mg or 60 mg daily

Matching Placebodrug

Drug: Matching Placebo Administration: Oral Dosage: 2 bottles daily