CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 359 enrolled
Drug / intervention
cCBT +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04419168
NCT04419168N/ACompleted

Cognitive Behavioral Therapy and Real-Time Pain Management Intervention for Sickle Cell Via Mobile Applications

University of Pittsburgh·interventional·Posted Jun 5, 2020·Updated Feb 19, 2025

In Brief

A clinical study evaluating cCBT and m-Education for Chronic Pain and 2 related conditions. Completed, enrolled 359 participants across 7 sites.

Detailed Summary

The investigators are conducting a comparative effectiveness trial among adult patients with sickle cell disease (SCD) who report chronic pain (N = 350), randomized to receive either mobile phone-delivered computerized cognitive behavioral therapy (cCBT; n = 175) or digital education (m-Education; n = 175). Both intervention groups will receive weekly (more frequent if requested or needed) follow-up with a health coach for at least 3 months to reinforce learned materials. Both groups will also use their mobile device to track daily pain, mood, and medication used for two-week periods at baseline and each of the follow-up points (3, 6 and 12 months). Participants will also be given access to a study-associated online support group page where members can discuss with other patients, issues participants faced and what skills were or could be used to address them. Participants will continue all routine care including opioid pain management and novel therapies.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedJun 5, 2020
Enrollment StartAug 12, 2020
Primary CompletionMay 31, 2023
Study CompletionDec 11, 2023
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 6.1 years ago

Interventions

cCBTother

A digital, internet-delivered, evidence-based chatbot programmed to deliver content for both cCBT.

m-Educationother

A digital, internet-delivered, evidence-based chatbot programmed to deliver content for both m-Education.