CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 150 enrolled
Drug / intervention
PRP injection in the endometriumbiological
Likely dose
PRP injection in the endometrium 20 mlfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

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Search/NCT04424160
NCT04424160N/ACompleted
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Effects of Intrauterine Platelet Rich Plasma (PRP) on Endometrium and Pregnancy Rates in Patients With Suboptimal Endometrium Undergoing Frozen Embryo Transfer

Acibadem University·interventional·Posted Jun 9, 2020·Updated Apr 20, 2021

In Brief

A clinical study evaluating PRP injection in the endometrium for Asherman Syndrome. Completed, enrolled 150 participants across 1 site.

Detailed Summary

Intrauterine platelet rich plasma will be injected in the endometrial region via the vaginal route after the cessation of menstrual period. The endometrial thickness will be assessed under ultrasound and hormone replacement will be started. As the endometrial thickness reaches adequate thickness during ultrasound follow-up, embryo transfer will be performed.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAsherman Syndrome
CountriesTurkey (Türkiye)
CollaboratorsBaskent University

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedJun 9, 2020
Enrollment StartSep 15, 2020
Primary CompletionApr 19, 2021
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 6.1 years ago

Interventions

PRP injection in the endometriumbiological

Within 5 days after the cessation of menstrual period, endometrial PRP procedure will be planned. Approximately 20 ml of blood sample will be collected under sterile conditions, and PRP will be prepared. The same day, within 2 hours of sample preparation, PRP injection will be performed transvaginally under ultrasound guidance and under sedation anesthesia into the endometrial region of the endometrium in several positions.On the same day after the procedure, the patient will be observed in the outpatient room and will be discharged on the same day.