CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 14,727 enrolled
Drug / intervention
RSVpreF +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04424316
NCT04424316Phase 3Completed

A PHASE 3, RANDOMIZED, DOUBLE-BLINDED, PLACEBO-CONTROLLED TRIAL TO EVALUATE THE EFFICACY AND SAFETY OF A RESPIRATORY SYNCYTIAL VIRUS (RSV) PREFUSION F SUBUNIT VACCINE IN INFANTS BORN TO WOMEN VACCINATED DURING PREGNANCY

Pfizer·interventional·Posted Jun 9, 2020·Updated Feb 11, 2025

In Brief

A Phase 3 clinical trial evaluating RSVpreF and Placebo for Respiratory Tract Infection. Completed, enrolled 14,727 participants across 464 sites in 18 countries.

Detailed Summary

This randomized, double-blinded, placebo-controlled Phase 3 study is designed to evaluate the efficacy and safety of maternal immunization with RSVpreF against medically attended lower respiratory tract illness (MA-LRTI) in infants.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesArgentina, Australia, Brazil, Canada, Chile, Denmark, Finland, Japan, Mexico, Netherlands, New Zealand, Philippines, South Africa, South Korea, Spain, Taiwan, The Gambia, United States
Collaborators--

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedJun 9, 2020
Enrollment StartJun 17, 2020
Primary CompletionOct 27, 2023
TodayJul 2, 2026
Enrollment to primary: 3.4 yearsPosted 6.1 years ago

Interventions

RSVpreFbiological

RSV vaccine (RSVpreF)

Placebobiological

Placebo