CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 100 enrolled
Drug / intervention
Pentacam tomographyother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04433936
NCT04433936N/ACompleted
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Corneal Tomographic Analysis Among Patients With Thyroid Gland Dysfunction.

Ameera Gamal Abdelhameed·observational·Posted Jun 16, 2020·Updated Jun 16, 2020

In Brief

An observational study evaluating Pentacam tomography for Keratoconus and 2 related conditions. Completed, enrolled 100 participants across 1 site.

Detailed Summary

The current study involved analysis of the corneal tomographic parameters of patients with thyroid gland dysfunction (hyperthyroidism or hypothyroidism), including those with an autoimmune etiology, in comparison to healthy controls without TGD, using pentacam, in an attempt to detect possible early corneal changes and to highlight whether early screening of those patients would be necessary for early detection of KC.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsKeratoconus, Corneal Ectasia, Thyroid Eye Disease
CountriesEgypt
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedJun 16, 2020
Enrollment StartFeb 1, 2018
Primary CompletionJun 1, 2018
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 6.0 years ago

Interventions

Pentacam tomographyother

The Pentacam maps were analyzed. The following anterior and posterior corneal surface parameters were evaluated by the Scheimpflug system: Kf, Ks, Kmax. The pachymetric map was analyzed, including CCT at the apex of the geometric center and CTmin. PPIavg, PPI min and PPI max were calculated . The Ambrósio relational thickness (ART) was calculated The posterior corneal elevation maps were evaluated and the posterior corneal elevation values relative to this reference were recorded. The back difference elevation and multimetric D index values were extrapolated from the difference map of the Belin/Ambrósio-enhanced ectasia display of the Pentacam system.