CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 27 enrolled
Drug / intervention
RO7297089drug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04434469
NCT04434469Phase 1Completed

An Open-Label, Multicenter, Phase I Trial Evaluating The Safety And Pharmacokinetics Of Escalating Doses Of RO7297089 In Patients With Relapsed Or Refractory Multiple Myeloma

Genentech, Inc.·interventional·Posted Jun 16, 2020·Updated Jul 3, 2024

In Brief

A Phase 1 clinical trial evaluating RO7297089 for Refractory Multiple Myeloma and Relapsed Multiple Myeloma. Completed, enrolled 27 participants across 10 sites in 4 countries.

Detailed Summary

This is a first-in-human Phase I, open-label, multicenter, global, dose-escalation study designed to evaluate the safety, tolerability, and pharmacokinetics of RO7297089 and make a preliminary assessment of anti-tumor activity in patients with R/R MM for whom no established therapy for MM is appropriate and available or who are intolerant to those established therapies.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Belgium, Denmark, Norway
Collaborators--

Timeline

Phase 1CompletedFinished
202120222023202420252026
First PostedJun 16, 2020
Enrollment StartJul 8, 2020
Primary CompletionFeb 23, 2022
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 6.0 years ago

Interventions

RO7297089drug

RO7297089 will be given via intravenous (IV) infusion