CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 162 enrolled
Drug / intervention
Zilucoplan +1 moredrug
Likely dose
Zilucoplan 0.3mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04436497
NCT04436497Phase 3Completed

HEALEY ALS Platform Trial - Regimen A Zilucoplan

Merit E. Cudkowicz, MD·interventional·Posted Jun 18, 2020·Updated Jul 25, 2023

In Brief

A Phase 3 clinical trial evaluating Zilucoplan and Matching Placebo for Amyotrophic Lateral Sclerosis. Completed, enrolled 162 participants across 1 site.

Detailed Summary

The HEALEY ALS Platform Trial is a perpetual multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investigational products for the treatment of ALS. Regimen A will evaluate the safety and efficacy of a single study drug, zilucoplan, in participants with ALS.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsRa Pharmaceuticals

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedJun 18, 2020
Enrollment StartJul 29, 2020
Primary CompletionApr 13, 2022
Study CompletionMay 4, 2022
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 6.0 years ago

Interventions

Zilucoplandrug

Drug: Zilucoplan Administration: Subcutaneous injection Dosage: 0.3mg/kg administered daily

Matching Placebodrug

Drug: Matching Placebo Administration: Subcutaneous injection Dosage: Daily subcutaneous injection