CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 200 enrolled
Drug / intervention
SAGE-217 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04442503
NCT04442503Phase 3Completed

A Randomized, Double-Blind, Placebo-controlled Study Evaluating the Efficacy and Safety of SAGE-217 in the Treatment of Adults With Severe Postpartum Depression

Biogen·interventional·Posted Jun 22, 2020·Updated Nov 30, 2023

In Brief

A Phase 3 clinical trial evaluating SAGE-217 and Placebo for Depression, Postpartum. Completed, enrolled 200 participants across 82 sites in 3 countries.

Detailed Summary

The purpose of this study is to determine if treatment with SAGE-217 reduces depressive symptoms in females with severe postpartum depression (PPD) as compared to placebo.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesSpain, United Kingdom, United States
Collaborators--

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedJun 22, 2020
Enrollment StartJun 8, 2020
Primary CompletionMar 15, 2022
Study CompletionApr 12, 2022
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 6.0 years ago

Interventions

SAGE-217drug

SAGE-217 oral capsules.

Placebodrug

SAGE-217 matched-placebo oral capsules.