CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 57 enrolled
Drug / intervention
ACI-35.030 +5 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04445831
NCT04445831Phase 2Completed

A Phase Ib/IIa Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Safety, Tolerability and Immunogenicity of Different Doses, Regimens and Combinations of Tau Targeted Vaccines in Subjects With Early Alzheimer's Disease

AC Immune SA·interventional·Posted Jun 24, 2020·Updated Feb 14, 2025

In Brief

A Phase 2 clinical trial evaluating ACI-35.030, Placebo, and 1 other intervention for Alzheimer's Disease and 6 related conditions. Completed, enrolled 57 participants across 9 sites in 4 countries.

Detailed Summary

This study is a multicenter, double blind, randomized, placebo-controlled study to evaluate the safety, tolerability and immunogenicity of different doses, regimens and combinations of Tau targeted vaccines in participants with early Alzheimer's Disease.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesFinland, Netherlands, Sweden, United Kingdom

Timeline

Phase 2CompletedFinished
2020202120222023202420252026
First PostedJun 24, 2020
Enrollment StartJul 31, 2019
Primary CompletionSep 5, 2023
TodayJul 2, 2026
Enrollment to primary: 4.1 yearsPosted 6.0 years ago

Interventions

ACI-35.030biological

Administration of a Low dose of ACI-35.030

ACI-35.030biological

Administration of a Medium dose of ACI-35.030

ACI-35.030biological

Administration of a High dose of ACI-35.030

Placeboother

Administration of Placebo

JACI-35.054biological

Administration of a Low dose of JACI-35.054

JACI-35.054biological

Administration of a Medium dose of JACI-35.054