CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 284 enrolled
Drug / intervention
Sitting in chair positionprocedure
Likely dose
Not stated in record
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Search/NCT04446559
NCT04446559N/ACompleted

Effect of " Sitting in a Chair " Versus " Conventional Semi-recumbent In-bed Position " on the Oxygenation Level for ICU Non-sedated Patients

Centre Hospitalier Régional d'Orléans·interventional·Posted Jun 25, 2020·Updated Aug 2, 2024

In Brief

A clinical study evaluating Sitting in chair position for ICU Patient. Completed, enrolled 284 participants across 1 site.

Detailed Summary

The positioning of the ICU patient is a daily concern of the medical and paramedical teams. Developments in emergency medicine and sedation and analgesia techniques have made it possible to reduce patient mortality. However, considered too unstable, patients were no longer mobilized outside the bed until the complete resolution of the symptoms that led to hospitalization or surgery. Despite encouraging results for early mobilization, bed and rest remained the most widespread positioning technique worldwide with the emergence of intensive care units, mechanical ventilation and sedation/analgesia/curarization. The result is peripheral muscular amyotrophy and respiratory muscular amyotrophy, with increased length of stay and exacerbated morbidity/mortality several years after discharge from ICU. Numerous studies have shown the value of early mobilization of the ICU patient to preserve functional and muscular capital. However, few studies have evaluated the value of mobilizing the ICU patient from the bed in order to improve oxygenation. The lack of mobility outside the bed causes condensation of the pulmonary parenchyma at the bases and in the dorsal region when the patient is lying down or in a prolonged semi-seated position. In awake spontaneously ventilated patients, whether intubated on ventilatory support (Pressure Support), non-invasive ventilation (NIV) or high flow nasal oxygen therapy (HFNO), the reference position is a semi-seated patient with the head of the resuscitation bed tilted at 30°. The problem with this position in the bed is that patients tend to slide toward the foot of the bed. This migration is due to gravity or the design of the ICU bed. The end result of this migration is that the inclination indicated by the bed head inclinometer does not correspond to the actual angulation between the patient's lower limbs and trunk. The patient finds himself "compressed" in the lower abdomen, which can lead to compression of the diaphragm and thus hypoventilation in the postero-caudal regions of the lungs. Our hypothesis is that the chair position (outside the ICU bed) allows, without modification of the ventilatory parameters, to improve the alveolar ventilation and thus the oxygenation of the arterial blood, compared to the "natural" semi-seated position in the ICU bed, in patients with spontaneous ventilation (PS/NIV/HFNO).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsICU Patient
CountriesFrance
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedJun 25, 2020
Enrollment StartJun 19, 2020
Primary CompletionJul 6, 2024
TodayJul 2, 2026
Enrollment to primary: 4.0 yearsPosted 6.0 years ago

Interventions

Sitting in chair positionprocedure

For patients randomized in the chair group, we will perform the transfer to the chair immediately after the morning arterial blood gas. The chair position will be maintained for 3 hours, if the patient shows no clinical signs of discomfort or intolerance.