CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 319 enrolled
Drug / intervention
LX9211 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04455633
NCT04455633Phase 2Completed

A Phase 2, Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of LX9211 in the Treatment of Diabetic Peripheral Neuropathic Pain

Lexicon Pharmaceuticals·interventional·Posted Jul 2, 2020·Updated Jun 25, 2025

In Brief

A Phase 2 clinical trial evaluating LX9211 and LX9211 Matching Placebo for Diabetic Peripheral Neuropathy and Diabetes. Completed, enrolled 319 participants across 44 sites.

Detailed Summary

Evaluation of the efficacy of a low and high dose of LX9211 compared to placebo in reducing pain related to diabetic peripheral neuropathy (DPNP) over an 11 week assessment period.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
202120222023202420252026
First PostedJul 2, 2020
Enrollment StartSep 3, 2020
Primary CompletionMay 23, 2022
Study CompletionJun 28, 2022
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 6 years ago

Interventions

LX9211drug

Oral Tablets

LX9211 Matching Placebodrug

Oral Tablets