CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 71 enrolled
Drug / intervention
Continuous Infusion +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04458467
NCT04458467N/ACompleted

Perineural Local Anesthetic Administration With a Continuous Infusion Versus Automatic Intermittent Boluses

University of California, San Diego·interventional·Posted Jul 7, 2020·Updated Jun 30, 2022

In Brief

A clinical study evaluating Continuous Infusion and Automated Intermittent Boluses for Pain, Acute and 2 related conditions. Completed, enrolled 71 participants across 1 site.

Detailed Summary

This will be a randomized comparison of continuous local anesthetic infusion with patient controlled boluses (PCA) to automated boluses with PCA for continuous popliteal sciatic nerve blocks. The goal will be to determine the relationship between method of local anesthetic administration (continuous with PCA initiated at discharge vs. intermittent dosing with PCA with a 5-hour delay) for continuous peripheral nerve block and the resulting pain control and duration of analgesia.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedJul 7, 2020
Enrollment StartJul 15, 2020
Primary CompletionMar 12, 2021
Study CompletionMar 16, 2021
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 6.0 years ago

Interventions

Continuous Infusiondevice

A continuous infusion of ropivacaine 0.2% (6 mL/hr, 4 mL patient controlled bolus with 30-minute lockout) will be initiated in the recovery room.

Automated Intermittent Bolusesdevice

Administration of automated intermittent boluses of ropivacaine 0.2% (8 mL every 2 hr with 4 mL patient controlled bolus with 30-minute lockout) will be initiated in the recovery room, but with a 5-hour delay for the first bolus (can be overridden by patients if they would like to initiate their perineural infusion earlier than 5 hours).