CI

At a glance

ClinicalIndex Comparison Record
Early Ph 1Completed· 20 enrolled
Drug / intervention
Dabigatran Etexilate Mesylate +1 moredrug
Likely dose
Dabigatran Etexilate Mesylate 150 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04459585
NCT04459585Early Ph 1Completed

A Phase 1, Open-Label, Fixed Sequence Drug Interaction Study to Evaluate the Potential Intestinal Inhibitory Effect of Quizartinib on the Pharmacokinetics of a Pgp Substrate Dabigatran Etexilate in Healthy Subjects

Daiichi Sankyo Co., Ltd.·interventional·Posted Jul 7, 2020·Updated Jul 9, 2021

In Brief

A Early Phase 1 clinical trial evaluating Dabigatran Etexilate Mesylate and Quizartinib for Healthy Subjects and 3 related conditions. Completed, enrolled 20 participants across 1 site.

Detailed Summary

The purpose of this study is to investigate the one-way drug-drug interaction potential of quizartinib on dabigatran etexilate in healthy adult participants.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Early Ph 1CompletedFinished
202120222023202420252026
First PostedJul 7, 2020
Enrollment StartAug 28, 2020
Primary CompletionOct 20, 2020
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 6.0 years ago

Interventions

Dabigatran Etexilate Mesylatedrug

Single oral 150 mg capsule dose

Quizartinibdrug

Single oral 60 mg dose of quizartinib administered as two 30 mg tablets (26.5 mg free base per tablet)