CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 38 enrolled
Drug / intervention
Gengigel Forte©device
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04467736
NCT04467736N/ACompleted

A Randomized Controlled Trial Evaluating Hyaluronic Acid As a Wound Healing Agent Following Alveolar Ridge Preservation

University Hospital, Ghent·interventional·Posted Jul 13, 2020·Updated Sep 19, 2024

In Brief

A clinical study evaluating Gengigel Forte© for Healing Wound. Completed, enrolled 38 participants across 1 site.

Detailed Summary

After tooth extraction, shrinkage of the bone is expected after 6 months. These changes may hamper dental implant placement and compromise soft tissue aesthetics. Alveolar Ridge Preservation (ARP) includes application of bovine-derived deproteinized bone particles in the extraction site. This technique is widely performed and drastically limits aforementioned volumetric changes. The amount of bone preservation following ARP is affected by the soft tissue barrier. In an open healing situation, it takes about 4 weeks to have complete soft tissue closure. Faster soft tissue closure could optimize the amount of bone preservation with obvious benefits for implant placement and aesthetics. Recent presentations showed the application of hyaluronic acid after ARP. However, no evidence can be found in the literature. This study aims to evaluate the wound healing potential of hyaluronic acid following ARP, as this has never been performed, yet seems promising from a biological point of view.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealing Wound
CountriesBelgium
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedJul 13, 2020
Enrollment StartAug 1, 2020
Primary CompletionJun 30, 2021
Study CompletionJan 24, 2022
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 6.0 years ago

Interventions

Gengigel Forte©device

Gengigel (hyaluronic acid) will be administered by the patient 3 times per day during 7 days following alveolar ridge preservation