CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 102 enrolled
Drug / intervention
Low Dose of KBP-COVID-19 +2 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04473690
NCT04473690Phase 2Completed

A Phase I/II, First-in-human, Observer-blinded, Randomized, Placebo-controlled, Parallel Group Study to Evaluate the Safety and Immunogenicity of TAP-COVID-19 SARS-CoV-2 Vaccine With CpG Adjuvant in Healthy Adults Aged 18-49 and 50-85

KBio Inc·interventional·Posted Jul 16, 2020·Updated May 18, 2025

In Brief

A Phase 2 clinical trial evaluating Low Dose of KBP-COVID-19, High Dose of KBP-COVID-19, and 1 other intervention for Covid19. Completed, enrolled 102 participants across 8 sites in 2 countries.

Detailed Summary

This is an First In Human (FIH), observer-blinded, randomized, placebo-controlled, parallel group study to evaluate the safety and immunogenicity of KBP-COVID-19 plus CPG adjuvant vaccine in healthy adult subjects in 2 age groups, Part A (18-49 years) and Part B (50-85 years).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCovid19
CountriesCanada, United States
Collaborators--

Timeline

Phase 2CompletedFinished
202120222023202420252026
First PostedJul 16, 2020
Enrollment StartDec 30, 2020
Primary CompletionMay 31, 2022
Study CompletionOct 14, 2022
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 6.0 years ago

Interventions

Low Dose of KBP-COVID-19biological

Low Dose of KBP-COVID-19 and adjuvant

High Dose of KBP-COVID-19biological

High Dose of KBP-COVID-19 and adjuvant

Placebobiological

Buffered saline solution