CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 14 enrolled / 14 target
Drug / intervention
SPF 30 or Higher Suncreen +5 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04479514
NCT04479514Phase 2CompletedUpdate Overdue (0.2/mo)Completion was 29mo ago
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Preventative Skin Care for Children Undergoing Targeted CNS Tumor Therapy

Dana-Farber Cancer Institute·interventional·Posted Jul 21, 2020·Updated Jun 12, 2026

In Brief

A Phase 2 clinical trial evaluating Warm Baths or Showers, Moisturizer, and 4 other interventions for Pediatric Cancer and 2 related conditions. Completed, enrolled 14 participants across 2 sites.

Signals

Enrollment appears stalled

Detailed Summary

This research study is examining a preventive skin care regimen for children diagnosed with a brain tumor and receiving anti-cancer therapy with a MEK, Pan-RAF, or BRAF inhibitor.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPediatric Cancer, CNS Tumor, Childhood, Skin Inflammation
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
202120222023202420252026
First PostedJul 21, 2020
Enrollment StartOct 1, 2020
Primary CompletionJan 1, 2024
Study CompletionFeb 15, 2025
TodayJul 2, 2026
Enrollment to primary: 3.3 yearsPosted 5.9 years ago

Arms & Interventions

Preventative Skin Care Routineexperimental

Participants will perform a preventative skin care routine that includes daily sun protection, daily gentle skin care and every-other-day dilute bleach baths for the duration of the study. Participants will receive skin examinations and complete a survey about their skin condition at the initial visit when anti-cancer treatment is started, at six weeks after the start of treatment, and at twelve weeks after the start of treatment.

Other: Warm Baths or ShowersOther: MoisturizerDrug: SPF 30 or Higher SuncreenOther: Sun Protective ClothingBehavioral: Limited Sun ExposureOther: Dilute bleach baths

Interventions

Warm Baths or Showersother

Daily warm baths or showers

Moisturizerother

moisturizers applied daily immediately after bathing

SPF 30 or Higher Suncreendrug

Mineral based sunscreen of SPF 30 or higher applied on a daily basis on all sun exposed areas.

Sun Protective Clothingother

Sun protective clothing worn when outdoors

Limited Sun Exposurebehavioral

Limit sun exposure during peak hours of 10am-4pm

Dilute bleach bathsother

Warm 10-15 minute dilute bleach baths every other day