CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 84 enrolled
Drug / intervention
MT-1186 +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04481789
NCT04481789Phase 1Completed

Clinical Pharmacology Study of Oral Edaravone in Healthy Adult Males (Drug Interaction Study and Preliminary Regimen-Finding Study)

Tanabe Pharma Corporation·interventional·Posted Jul 22, 2020·Updated May 22, 2026

In Brief

A Phase 1 clinical trial evaluating MT-1186, Rosuvastatin, and 2 other interventions for Healthy Adult Subjects. Completed, enrolled 84 participants across 1 site.

Detailed Summary

* Cohort 1: To evaluate the drug interactions, safety, and tolerability of oral edaravone when coadministered with rosuvastatin, sildenafil or furosemide in healthy adult males * Cohort 2: To evaluate the pharmacokinetics, safety, and tolerability of oral edaravone in healthy Japanese and Caucasian adult males

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesJapan
Collaborators--

Timeline

Phase 1CompletedFinished
20192020202120222023202420252026
First PostedJul 22, 2020
Enrollment StartOct 17, 2018
Primary CompletionDec 20, 2018
Study CompletionJan 8, 2019
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 5.9 years ago

Interventions

MT-1186drug

Suspension

Rosuvastatindrug

Tablets

Sildenafildrug

Tablets

Furosemidedrug

Tablets