CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 127 enrolled
Drug / intervention
Cryoneurolysis +1 moreradiation
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04482582
NCT04482582N/ACompleted

Early Percutaneous Cryoablation for Pain Control After Rib Fractures Among Elderly Patients

Stanford University·interventional·Posted Jul 22, 2020·Updated Mar 27, 2026

In Brief

A clinical study evaluating Cryoneurolysis and Standard of Care for Rib Fractures. Completed, enrolled 127 participants across 1 site.

Detailed Summary

The purpose of this study is to provide long-term pain control for elderly patients with rib fractures in order to minimize their risk of complications and return them to baseline functional capacity

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRib Fractures
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedJul 22, 2020
Enrollment StartJun 1, 2021
Primary CompletionApr 25, 2024
Study CompletionApr 30, 2025
TodayJul 2, 2026
Enrollment to primary: 2.9 yearsPosted 5.9 years ago

Interventions

Cryoneurolysisradiation

Patients will be offered a minimally invasive solution known as cryoneurolysis. By directly applying a cold cryoneurolysis probe to the nerves the axon is destroyed, resulting in Wallerian degeneration of the distal nerve without distorting epineurial or perineurial tissue. Application of cryoneurolysis will help reduce the amount of narcotics the patient would need to take and instead provide them longer term pain control with minimal risk.

Standard of Careother

Patients will be provided regular standard of care at the Stanford Hospital with long-term follow-up provided at the Stanford Center for Reconstruction after Chest Wall Injury.