CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 44 enrolled
Drug / intervention
Tecovirimat +4 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04485039
NCT04485039Phase 4Completed

A Post-Marketing Open-Label, 5 Period Crossover, Drug-Drug Interaction Study of Orally Adminstered TPOXX When Co-administered With 4 Different Phosphate Binders in Healthy Subjects

SIGA Technologies·interventional·Posted Jul 24, 2020·Updated Dec 27, 2024

In Brief

A Phase 4 clinical trial evaluating Tecovirimat, sevelamer carbonate oral tablet, and 3 other interventions for Smallpox. Completed, enrolled 44 participants across 1 site.

Detailed Summary

An open-label, drug-drug interaction study with TPOXX and phosphate binders.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSmallpox
CountriesUnited States

Timeline

Phase 4CompletedFinished
202120222023202420252026
First PostedJul 24, 2020
Enrollment StartJun 8, 2022
Primary CompletionDec 15, 2022
Study CompletionApr 23, 2023
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 5.9 years ago

Interventions

Tecovirimatdrug

oral antiviral

sevelamer carbonate oral tabletdrug

phosphate binder

sucroferric oxyhydroxide chewable tabletdrug

phosphate binder

calcium acetate oral tabletdrug

phosphate binder

Lanthanum Carbonate Chewable Tabletdrug

phosphate binder