At a glance
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Social Reward and Its Effect on Brain Functions in Psychotherapies for Mid- and Late-Life Depression
In Brief
A clinical study evaluating "Engage & Connect" Psychotherapy and Symptom Review and Psychoeducation (SRP) for Major Depressive Disorder. Completed, enrolled 64 participants across 1 site.
Detailed Summary
Abnormalities in the Positive Valence System (PVS) are associated with depressive symptoms and reduced behavioral activation in mid- and late-life. This study will investigate the engagement of the PVS during exposure to social rewards, part of a novel streamlined psychotherapy for mid- and late-life depression. Use of computational modeling will enable identification of neuroimaging and behavioral profiles associated with greater treatment response, and may guide future personalization of psychotherapy.
Study Details
Timeline
Interventions
9-weeks of weekly psychotherapy sessions focused on social reward exposure
9-weeks of weekly psychotherapy sessions focused on symptom review and psychoeducation about depression and aging