CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 554 enrolled
Drug / intervention
ATH-1017 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04488419
NCT04488419Phase 3Completed

A Randomized, Placebo-Controlled, Double-Blind Study of ATH-1017 Treatment in Subjects With Mild to Moderate Alzheimer's Disease

LeonaBio·interventional·Posted Jul 28, 2020·Updated Apr 4, 2025

In Brief

A Phase 3 clinical trial evaluating ATH-1017 and Placebo for Alzheimer Disease and Dementia of Alzheimer Type. Completed, enrolled 554 participants across 1 site.

Detailed Summary

This study is designed to evaluate safety and efficacy of fosgonimeton (ATH-1017) in the treatment of mild to moderate Alzheimer's disease with a randomized treatment duration of 26-weeks.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedJul 28, 2020
Enrollment StartSep 28, 2020
Primary CompletionJul 15, 2024
TodayJul 2, 2026
Enrollment to primary: 3.8 yearsPosted 5.9 years ago

Interventions

ATH-1017drug

Daily subcutaneous (SC) injection of ATH-1017 in a pre-filled syringe

Placebodrug

Daily subcutaneous (SC) injection of Placebo in a pre-filled syringe