CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 207 enrolled
Drug / intervention
HBVAXPRO™biological
Likely dose
HBVAXPRO™ 0.5 mLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04490499
NCT04490499Phase 3Completed

A Hepatitis B Vaccine Challenge Study to Demonstrate the Durability of Protection Against Hepatitis B Virus Infection in Healthy Children Vaccinated Approximately 9 Years Previously With a 2- or 3-Dose Infant Series and Toddler Dose of Vaxelis®

Merck Sharp & Dohme LLC·interventional·Posted Jul 29, 2020·Updated Jul 27, 2022

In Brief

A Phase 3 clinical trial evaluating HBVAXPRO™ for Hepatitis B. Completed, enrolled 207 participants across 10 sites.

Detailed Summary

The purpose of this study is to demonstrate the durability of protection against hepatitis B virus (HBV) infection approximately 8-9 years after vaccination with Vaxelis®. This is an estimation study, and no formal hypothesis testing was performed.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHepatitis B
CountriesFinland
Collaborators--

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedJul 29, 2020
Enrollment StartSep 2, 2020
Primary CompletionDec 29, 2020
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 5.9 years ago

Interventions

HBVAXPRO™biological

Single 0.5 mL intramuscular dose