CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 135 enrolled
Drug / intervention
PD-L1 Kitother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04490564
NCT04490564N/ACompleted

A Clinical Performance Study to Validate the Use of Novel Molecular Diagnostic Assays for the Detection of Cancer Biomarkers in Peripheral Blood and Primary Tumor Tissue of Patients With Recurrent/Metastatic HNSCC, NSCLC or Melanoma.

Pharmassist Ltd·observational·Posted Jul 29, 2020·Updated Dec 30, 2025

In Brief

An observational study evaluating PD-L1 Kit for Head and Neck Squamous Cell Carcinoma and 2 related conditions. Completed, enrolled 135 participants across 6 sites.

Detailed Summary

Conventional biopsy and surgical tumor resection are invasive procedures that capture only one instance of the progression of the tumor. However, the genome of tumor is not static, but it is constantly altered during treatment. Liquid biopsy is a non-invasive approach based on the extraction of information through peripheral blood analysis. It makes it possible to characterize the development of a solid tumor in real time, through detailed molecular analysis of circulating genetic material in peripheral blood.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesGreece

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedJul 29, 2020
Enrollment StartJun 25, 2019
Primary CompletionSep 7, 2022
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 5.9 years ago

Interventions

PD-L1 Kitother

Clinical performance of PD-L1 kit in CTCs of peripheral blood and tumor tissue samples