CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 35 enrolled
Drug / intervention
Gene Expressionother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04497727
NCT04497727N/ACompleted

Gut Inflammation and Gut-Gut Microbiome Interactions in the Pathogenesis of Hypertension

University of Florida·observational·Posted Aug 4, 2020·Updated Sep 29, 2025

In Brief

An observational study evaluating Gene Expression for Gut Inflammation and Hypertension. Completed, enrolled 35 participants across 1 site.

Detailed Summary

The study compared basic properties of gut epithelia of hypertensive and normotensive reference subjects. The study determined if there are fundamental differences in the gut epithelium in hypertension compared to normotension. Specifically, this study examined gene expression profiles of gut organoids derived from biopsy samples of hypertensive and normotensive individuals undergoing clinically indicated colonoscopy.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedAug 4, 2020
Enrollment StartMar 5, 2021
Primary CompletionApr 8, 2022
Study CompletionApr 21, 2024
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 5.9 years ago

Interventions

Gene Expressionother

Gene expression analysis of biopsy specimens obtained during routine colonoscopy examination