CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 180 enrolled
Drug / intervention
Dietary interventionother
Likely dose
Not stated in record
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Search/NCT04497974
NCT04497974N/ACompleted

Role of Long-term Dietary Sweetness Exposure on Sweetness Preferences

Wageningen University·interventional·Posted Aug 4, 2020·Updated Jun 13, 2024

In Brief

A clinical study evaluating Dietary intervention for Food Preferences. Completed, enrolled 180 participants across 1 site.

Detailed Summary

In recent years, social pressure has been exerted towards lowering sugar and sweetness levels in foods, with the aim of decreasing the sweetness preference of the general population. However, the resilience/flexibility of sweetness preferences and the impact on energy intake is a fundamental knowledge gap. Recent, relatively long-term studies limited to no more than 3 months did not find a relationship between sweetness exposure and sweetness preferences. Therefore, a longer-term systematic investigation is necessary to objectively evaluate whether sweetness preferences can be altered via varying the sweetness exposure and whether it can affect other outcomes, such as perceived taste intensity, food intake, body weight, body composition, glucose homeostasis and sweet liker type. The study sample will consist of 180 subjects. Enrolled participants will be distributed into three intervention groups; regular dietary sweetness exposure (n=60); low dietary sweetness exposure (n=60); and high dietary sweetness exposure (n =60). The intervention is semi-controlled for a period of six months. Preference and perceived taste intensity of a series of familiar and unfamiliar foods will be assessed at baseline (Day 0), during the intervention (Month 1, Month 3, Month 6) and in the follow-up period (Month 7, Month 10). Furthermore, outcomes such as observed food choice and intake during a test meal, reported food preferences, reported food cravings, sweet-liker type, glucose homeostasis, body weight, body composition and biomarkers related to diabetes and cardiovascular disease will be assessed as well.

Study Details

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedAug 4, 2020
Enrollment StartOct 20, 2020
Primary CompletionJun 5, 2024
TodayJul 2, 2026
Enrollment to primary: 3.6 yearsPosted 5.9 years ago

Interventions

Dietary interventionother

Varying the exposure to sweetness via diet manipulation.