CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 1,180 enrolled
Drug / intervention
Bamlanivimab +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04497987
NCT04497987Phase 3Completed

A Phase 3 Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of LY3819253 Alone and in Combination With LY3832479 in Preventing SARS-CoV-2 Infection and COVID-19 in Skilled Nursing and Assisted Living Facility Residents and Staff; a NIAID and Lilly Collaborative Study

Eli Lilly and Company·interventional·Posted Aug 4, 2020·Updated Feb 4, 2022

In Brief

A Phase 3 clinical trial evaluating Bamlanivimab, Placebo, and 1 other intervention for COVID-19 and SARS-CoV2. Completed, enrolled 1,180 participants across 27 sites.

Detailed Summary

The purpose of this study is to evaluate whether LY3819253 given alone and with LY3832479 prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease - 2019 (COVID-19). Facility staff and residents in contracted skilled nursing and assisted living facility networks with a high risk of SARS-CoV-2 exposure will receive LY3819253, LY3819253 and LY3832479, or placebo via an injection into a vein. Samples will be taken from the nose. Blood samples will be drawn. Participation could last up to 25 weeks and may include up to 19 visits.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCOVID-19, SARS-CoV2
CountriesUnited States

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedAug 4, 2020
Enrollment StartAug 2, 2020
Primary CompletionJan 16, 2021
Study CompletionMay 20, 2021
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 5.9 years ago

Interventions

Bamlanivimabdrug

Administered IV.

Placebodrug

Administered IV.

Etesevimabdrug

Administered IV.