At a glance
ClinicalIndex Comparison Record- ✓Adults aged 18 or over
- ✓New diagnosis of oropharyngeal cancer, all anatomical subsites and HPV status accepted
- ✓Unilateral metastatic nodes N1-N2b (HPV-negative) or N1 (HPV-positive)
- ✕Suspicious bilateral nodes on imaging
- ✕Previous radiotherapy or surgery to the neck
- ✕Second primary oropharyngeal tumours
- ✕Distant metastasis (e.g. lung, bone)
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Prospective, Multi-Centre, Phase II Validation Study for a Lymphatic Imaging Protocol in Establishing Drainage Patterns in Patients With Oropharyngeal Cancer
In Brief
A clinical study evaluating Imaging procedure and Surgical procedure for Oropharyngeal Cancer. Currently recruiting, targeting 150 participants across 2 sites.
Signals
Detailed Summary
A multi-centre validation study to evaluate whether a new imaging and surgical protocol would work as well as the current gold standard in identifying sentinel nodes in patients with oropharyngeal cancer.
Study Details
Timeline
Interventions
During routine examination under anaesthetic 4 x peritumoural injection of investigator's choice of 99mTc-human albumin colloidal particles or Lymphoseek (lymphatic mapping tracer) followed by freehand SPECT scan
Excision of contralateral nodes identified on imaging \*(fhSPECT or SPECT/CT\*) during routine examination under anaesthetic. Serial sectioning of excised (sentinel) nodes to identify micrometastasis.