CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 10 enrolled
Drug / intervention
Combined Non-invasive brain stimulation and functional electrical hand stimulationdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04502290
NCT04502290N/ACompleted

Synchronized Brain and Hand Stimulation to Improve Hand Function After Stroke

Amit Sethi·interventional·Posted Aug 6, 2020·Updated Jul 15, 2025

In Brief

A clinical study evaluating Combined Non-invasive brain stimulation and functional electrical hand stimulation for Stroke and Upper Extremity Paresis. Completed, enrolled 10 participants across 1 site.

Detailed Summary

Among the 795,000 individuals who sustain a stroke annually in the United States, 65% continue to experience moderate-to-severe impairments in one hand six months or more, which limits their ability to perform daily tasks. Currently there is dearth of understanding of the mechanisms of motor recovery after stroke. Understanding the mechanisms can potentially lead to the development of interventions to improve motor performance after stroke. The proposed study will examine how synchronously pairing brain and hand stimulation repeatedly affects the plasticity of the brain and motor performance after stroke. The knowledge gained from this study can be useful to develop interventions to improve hand movement after moderate-severe stroke.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedAug 6, 2020
Enrollment StartOct 1, 2020
Primary CompletionMay 22, 2024
TodayJul 2, 2026
Enrollment to primary: 3.6 yearsPosted 5.9 years ago

Interventions

Combined Non-invasive brain stimulation and functional electrical hand stimulationdevice

Participants will receive synchronously combined non-invasive brain stimulation (delivered via electrical/magnetic stimulation) with functional electrical stimulation (delivered via DS7A or Neuromove) of the weak hand