CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 78 enrolled
Drug / intervention
Acupuncture Therapy +4 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04505553
NCT04505553Phase 2Completed

Pilot Study of Oral Cryotherapy vs. Oral Cryotherapy Plus Acupuncture and Acupressure to Decrease Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy for GI Cancers

University of Washington·interventional·Posted Aug 10, 2020·Updated Jan 21, 2026

In Brief

A Phase 2 clinical trial evaluating Acupuncture Therapy, Acupressure Therapy, and 3 other interventions for Appendix Carcinoma and 12 related conditions. Completed, enrolled 78 participants across 1 site.

Detailed Summary

This phase II trial investigates how well oral cryotherapy plus acupressure and acupuncture compared with oral cryotherapy alone work in decreasing chemotherapy-induced peripheral neuropathy in patients with gastrointestinal cancer who are receiving oxaliplatin-based chemotherapy. Acupressure is the application of pressure or localized massage to specific sites on the body to control symptoms such as pain or nausea. Acupuncture is the technique of inserting thin needles through the skin at specific points on the body to control pain and other symptoms. Cryotherapy uses cold temperature such as oral ice chips to prevent abnormally increased pain sensation. Giving oral cryotherapy with acupressure and acupuncture may work better in decreasing chemotherapy-induced peripheral neuropathy from oxaliplatin-based chemotherapy in patients with gastrointestinal cancer compared to oral cryotherapy alone.

Study Details

Timeline

Phase 2CompletedFinished
202120222023202420252026
First PostedAug 10, 2020
Enrollment StartJun 1, 2021
Primary CompletionMar 7, 2024
Study CompletionMar 31, 2024
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 5.9 years ago

Interventions

Acupuncture Therapyprocedure

Undergo acupuncture

Acupressure Therapyprocedure

Undergo acupressure

Oral Cryotherapyprocedure

Undergo oral cryotherapy

Questionnaire Administrationother

Ancillary studies

Quality-of-Life Assessmentother

Ancillary studies