CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 1,410 enrolled
Drug / intervention
Best practice alert for the notification of patient HFrEF and recommended evidence-based therapies (NO drugs are being administered in this trial)other
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04514458
NCT04514458N/ACompleted
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Pragmatic Trial of Messaging to Providers About Treatment of Heart Failure

Yale University·interventional·Posted Aug 17, 2020·Updated Jul 1, 2025

In Brief

A clinical study evaluating Best practice alert for the notification of patient HFrEF and recommended evidence-based therapies (NO drugs are being administered in this trial) for Heart Failure With Reduced Ejection Fraction. Completed, enrolled 1,410 participants across 1 site.

Detailed Summary

A randomized controlled trial to compare the efficacy of an electronic health record-based alert informing providers about evidence-based medications for HFrEF versus usual care (no alert) in outpatient clinics across a single health system.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHeart Failure With Reduced Ejection Fraction
CountriesUnited States
CollaboratorsAstraZeneca

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedAug 17, 2020
Enrollment StartJan 25, 2021
Primary CompletionNov 20, 2021
Study CompletionOct 20, 2022
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 5.9 years ago

Interventions

Best practice alert for the notification of patient HFrEF and recommended evidence-based therapies (NO drugs are being administered in this trial)other

Providers will receive a best practice alert for each of their eligible patients upon opening of the order entry screen in the patient's medical record. The alert will inform the provider to the presence of HFrEF and of the patient's current left ventricular ejection fraction and current evidence-based medications for HFrEF. It will also provide access to an order set with recommended evidence-based HFrEF therapies as well as a link to the best available guideline-recommended information regarding the treatment of heart failure.