CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 45 enrolled
Drug / intervention
Safety Aid Reduction Treatment for PTSDbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04515784
NCT04515784N/ACompleted

Examination of a Safety Aid Reduction Protocol for Treatment Resistant PTSD Among Veterans

VA Office of Research and Development·interventional·Posted Aug 17, 2020·Updated Nov 13, 2025

In Brief

A clinical study evaluating Safety Aid Reduction Treatment for PTSD for Stress Disorders, Post-Traumatic. Completed, enrolled 45 participants across 1 site.

Detailed Summary

The purpose of this project is to examine the acceptability, feasibility, and utility of a safety aid reduction treatment (START) among Veterans with posttraumatic stress disorder (PTSD). It is hypothesized that START will be acceptable, feasible, and will lead to reductions in PTSD symptom severity immediately and over time.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedAug 17, 2020
Enrollment StartSep 23, 2024
Primary CompletionSep 29, 2025
Study CompletionSep 30, 2025
TodayJul 2, 2026
Enrollment to primary: 1.0 yearsPosted 5.9 years ago

Interventions

Safety Aid Reduction Treatment for PTSDbehavioral

START-PTSD includes many of the key elements found in empirically supported treatments for PTSD including: a) psychoeducation regarding the development and maintenance of PTSD; and b) exposure to internal sensations and external situations that are connected to one's fear/distress response via identification and elimination of safety aids. Known safety aids to be covered include: cognitive avoidance (e.g., using mental distractions to avoid trauma-related images); situational avoidance (e.g., avoiding crowded market places); checking behaviors (e.g., checking doors, windows, locks, and perimeters more often than necessary); reassurance seeking (e.g., excessively watching the news); other compulsive behaviors (e.g., checking the location of exits); use of companions (e.g., relying on someone to attend a social gathering); and use of alcohol and certain substances (e.g., consuming alcohol to reduce anxiety).