CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 75 enrolled / 75 target
Drug / intervention
Avatrombopag +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04516967
NCT04516967Phase 3CompletedMonitor (1.2/mo)Completion was 31mo ago

Randomized, Double-blind, Placebo-controlled Study With Open-label Extension Phase to Evaluate the Efficacy and Safety of Avatrombopag for the Treatment of Thrombocytopenia in Pediatric Subjects With Immune Thrombocytopenia for ≥6 Months

Sobi, Inc.·interventional·Posted Aug 18, 2020·Updated Jun 3, 2026

In Brief

A Phase 3 clinical trial evaluating Avatrombopag and Placebo for Immune Thrombocytopenia. Completed, enrolled 75 participants across 62 sites in 9 countries.

Signals

Enrolling slower than its timeline implies

Detailed Summary

A Phase 3b Study to Evaluate the Efficacy and Safety of Avatrombopag for the Treatment of Thrombocytopenia in Pediatric Subjects with Immune Thrombocytopenia for ≥6 Months

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesFrance, Germany, Hungary, Poland, Russia, Turkey (Türkiye), Ukraine, United Kingdom, United States
Collaborators--

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedAug 18, 2020
Enrollment StartMar 5, 2021
Primary CompletionNov 8, 2023
Study CompletionOct 28, 2025
TodayJul 2, 2026
Enrollment to primary: 2.7 yearsPosted 5.9 years ago

Arms & Interventions

Experimental: Avatrombopag Double Blindexperimental

Study is 3:1 randomization ratio (avatrombopag to placebo). Investigational product administered orally once daily for 12 weeks

Drug: Avatrombopag
Placebo Comparator:Placebo Double Blindplacebo_comparator

Study is 3:1 randomization ratio (avatrombopag to placebo). Investigational product administered orally once daily for 12 weeks

Drug: Placebo
Avatrombopag Open Label Extensionexperimental

Investigational product administered orally for up to 2 years.

Drug: Avatrombopag

Interventions

Avatrombopagdrug

Oral avatrombopag tablet or sprinkle capsule

Placebodrug

Placebo comparator tablet or sprinkle capsule