CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 22 enrolled
Drug / intervention
2.5 g of lidocaine 23% / tetracaine 7% ointment without occlusion +1 moredrug
Likely dose
2.5 g of lidocaine 23% / tetracaine 7% ointment without occlusionfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04523961
NCT04523961Phase 3Completed

Prospective, Randomized, Double-blinded, Split-face Study Comparing Efficacy of Lidocaine 2.5%/Prilocaine 2.5% Cream Under Occlusion, and Lidocaine 23% /Tetracaine 7% Ointment for Anesthesia Prior to 1927nm Fractional Laser Treatment

Mayo Clinic·interventional·Posted Aug 24, 2020·Updated Feb 20, 2026

In Brief

A Phase 3 clinical trial evaluating 2.5 g of lidocaine 23% / tetracaine 7% ointment without occlusion and 7.5 g lidocaine 2.5%/ prilocaine 2.5% cream with occlusion for Anesthesia, Local and 2 related conditions. Completed, enrolled 22 participants across 1 site.

Detailed Summary

The purpose of this study is to determine the efficacy of lidocaine 2.5%/prilocaine 2.5% cream versus lidocaine 23%/tetracaine 7% ointment for topical anesthesia prior to a nonablative laser procedure.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
202120222023202420252026
First PostedAug 24, 2020
Enrollment StartJan 8, 2021
Primary CompletionFeb 19, 2025
TodayJul 2, 2026
Enrollment to primary: 4.1 yearsPosted 5.9 years ago

Interventions

2.5 g of lidocaine 23% / tetracaine 7% ointment without occlusiondrug

Topical anesthetic used to numb the skin prior to laser procedures

7.5 g lidocaine 2.5%/ prilocaine 2.5% cream with occlusiondrug

Topical anesthetic used to numb the skin prior to laser procedures