At a glance
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The Effect of Intraoperative Lidocaine Infusion and Intraoperative Lidocaine Combined With Ketamine Infusion on Opioid Consumption After Laparoscopic Bariatric Surgery: A Randomized Controlled Trial
In Brief
A Phase 4 clinical trial evaluating Lidocaine Hydrochloride, Ketamine, and 1 other intervention for Laparoscopic Bariatric Surgery. Completed, enrolled 87 participants across 1 site.
Detailed Summary
The most effective long-term treatment for obesity is bariatric surgery, however, postoperative pain control is challenging in these group of population. Opioid-sparing technique with multimodal analgesia is recommended but the evidence supported is still limited. Multimodal analgesia, particularly lidocaine and ketamine, has been used effectively in various type of surgery. However, the evidence supported their use in obese patients undergoing bariatric surgery is limited.
Study Details
Timeline
Interventions
lidocaine will be given 1.5 mg/kg bolus at induction then 2mg/kg/hr until the end of surgery.
Ketamine will be given 0.35 mg/kg bolus at induction then 0.2 mg/kg/hr until the end of surgery.
Normal saline will be given with the same rate of lidocaine or ketamine.