CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 14 enrolled
Drug / intervention
Virtual Reality-based Interactive Cognitive Training Program +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04526639
NCT04526639N/ACompleted
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Virtual Reality-based Rehabilitation for Pediatric TBI (R00 Phase)

University of Massachusetts, Lowell·interventional·Posted Aug 26, 2020·Updated Oct 16, 2025

In Brief

A clinical study evaluating Virtual Reality-based Interactive Cognitive Training Program and Placebo Virtual Reality Game for TBI (Traumatic Brain Injury). Completed, enrolled 14 participants across 2 sites.

Detailed Summary

Childhood traumatic brain injury (TBI) poses significant impairment in children's executive functions (EFs) for moderate to severe injuries, yet interventions specifically designed for children's EF rehabilitation post-TBI and rigorous clinical trials to establish the efficacy of such interventions remain unavailable. In this study, the investigators will conduct a randomized clinical trial to evaluate the efficacy of a novel virtual reality (VR)-based training program for EF rehabilitation for childhood TBI.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTBI (Traumatic Brain Injury)
CountriesUnited States
CollaboratorsSpaulding Rehabilitation Hospital, Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedAug 26, 2020
Enrollment StartSep 3, 2021
Primary CompletionAug 31, 2024
TodayJul 2, 2026
Enrollment to primary: 3.0 yearsPosted 5.9 years ago

Interventions

Virtual Reality-based Interactive Cognitive Training Programbehavioral

Three virtual reality-based games designed to train inhibitory control, working memory, and cognitive flexibility among children with TBI

Placebo Virtual Reality Gamebehavioral

A virtual playground for control group to interact without training executive functions