CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 13 enrolled
Drug / intervention
Ripretinib +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04530981
NCT04530981Phase 1Completed

A Phase 1 Open-label, Multicenter Study to Evaluate the Effect of Ripretinib on the Pharmacokinetics of a CYP2C8 Probe Substrate (Repaglinide) in Patients with Advanced Gastrointestinal Stromal Tumors (GIST)

Deciphera Pharmaceuticals, LLC·interventional·Posted Aug 28, 2020·Updated Sep 19, 2024

In Brief

A Phase 1 clinical trial evaluating Ripretinib and Repaglinide for GIST - Gastrointestinal Stromal Tumor. Completed, enrolled 13 participants across 3 sites.

Detailed Summary

Evaluate the Effect of Ripretinib on the Pharmacokinetics of a CYP2C8 Substrate

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 1CompletedFinished
202120222023202420252026
First PostedAug 28, 2020
Enrollment StartSep 22, 2021
Primary CompletionNov 16, 2023
Study CompletionJul 29, 2024
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 5.8 years ago

Interventions

Ripretinibdrug

Oral KIT/PDGFRA kinase inhibitor

Repaglinidedrug

Oral antihyperglycemic agent