CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 5,176 enrolled
Drug / intervention
Opt-outbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04536038
NCT04536038N/ACompleted

The Effect of opt-in Versus Opt-out Framing on Clinical Trial Enrollment Among Patients With Peripheral Artery Disease

University of Pennsylvania·interventional·Posted Sep 2, 2020·Updated Dec 24, 2025

In Brief

A clinical study evaluating Opt-out for Peripheral Artery Disease. Completed, enrolled 5,176 participants across 1 site.

Detailed Summary

It is uncertain whether opt-out framing will increase participation in a clinical trial intended to promote physical activity in patients with peripheral artery disease (PAD). This study will test whether opt-in or opt-out framing of study participation upon initial contact affects the proportion of patients who ultimately enroll in the study and the demographic characteristics of enrolled patients.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedSep 2, 2020
Enrollment StartOct 5, 2020
Primary CompletionMay 31, 2023
Study CompletionJan 8, 2024
TodayJul 2, 2026
Enrollment to primary: 2.7 yearsPosted 5.8 years ago

Interventions

Opt-outbehavioral

A study coordinator will call the patient unless they opt-out. See arm description for more details.