CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 11 enrolled
Drug / intervention
Stereotactic Radiosurgery +2 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04545814
NCT04545814N/ACompleted
CompareCT.gov

A Pilot Study Analyzing Preoperative Stereotactic Radiosurgery (SRS) With Gamma Knife (GK) for Brain Metastases

Medical College of Wisconsin·interventional·Posted Sep 11, 2020·Updated Mar 24, 2026

In Brief

A clinical study evaluating Stereotactic Radiosurgery, Surgical Resection, and 1 other intervention for Brain Metastases. Completed, enrolled 11 participants across 1 site.

Detailed Summary

This is a single-arm, single-center pilot study in which 10 patients with one to four brain metastases diagnosed on brain magnetic resonance imaging (MRI) within the past 30 days will be evaluated for study eligibility and enrolled as appropriate.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBrain Metastases
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedSep 11, 2020
Enrollment StartJan 15, 2021
Primary CompletionAug 22, 2024
TodayJul 2, 2026
Enrollment to primary: 3.6 yearsPosted 5.8 years ago

Interventions

Stereotactic Radiosurgerydevice

Maximum Tumor Diameter ≤ 2 cm = 20-24 Gy; Maximum Tumor Diameter 2.1-3.0 cm = 18 Gy; Maximum Tumor Diameter 3.1-5.0 cm = 15 Gy

Surgical Resectionprocedure

Enrolled patients will receive GK-SRS to all metastases followed by surgical resection of resectable metastases within one to10 days following GK-SRS.

Magnetic Resonance Imagingdevice

Following surgical resection, the patient will enter a standard pattern of surveillance (brain MRI every three months for two years).